京都府立医科大学發現控制肥胖基因

Last month the FNN News on-line reported the following:

京都府立医大、肥満をコントロールする遺伝子の仕組み発見

京都府立医科大学の研究グループが、肥満やメタボリック症候群をコントロールする遺伝子の仕組みを発見したと発表した。
京都府立医大の池田宏二助教らは、研究対象の「ARIA」という遺伝子に、太る課程で、脂肪の中に新しい血管ができるのを抑え、脂肪の燃焼を妨げる働きがあることを突き止めた。
マウスを使った実験で、ARIAの働きが抑えられたマウスは太りにくく、通常より皮下脂肪や内臓脂肪が少なかったという。
池田助教は「(人の)ARIAの発現を見たところでは、非常にマウスで見た発現パターンと似ていますので、脂肪での発現が多いところも含めて、人でも同じようなことがいえる可能性が十二分にあるのではないかと考えています」と話した。
今後、この遺伝子の働きを抑える新薬が開発されれば、肥満などの画期的な治療法になるという。

(試譯文)

A research group in Kyoto Prefecture University of Medicine announced that they discovered the structure of the gene which controlled overweight and metabolic syndrome.

Assistant Professor Koji Ikeda of the Kyoto Prefecture University of Medicine traced the gene "ARIA" for research had ascertained that in the course of growing fat, ARIA stopped the growth of new blood vessels in the fat, and barred the burning of fat.

In the experiment using a mouse, the mouse that had the functioning of ARIA being suppressed could not grow fat easily, and it was said that subcutaneous fat and visceral fat were less than usual.

Assistant Professor Ikeda said, "in the discovered situation of ARIA (in human), the expression pattern observed is very much resembled with that of the mouse, including the many discovery in fat. Because of that, I think there is a very high possibility to say that the situation is the same in human".

From now on if a new medicine which might suppress the functioning of this gene could be developed, it could be said that it was be an epoch-making cure, such as for overweight.

I think to those people with overweight problems, the invention of this new drug could be good news.